The treatments guide

GLP-1 medications

Prescription medications (such as semaglutide and tirzepatide) for chronic weight management in eligible adults.

Awaiting clinical review. Written carefully from the sources below, but not yet signed off by a qualified clinician. Please don't use it to make decisions about your health. How we review.

Strong evidence

What the evidence says

Strong trial evidence for weight loss alongside lifestyle changes in eligible adults. Side effects are common, and weight often returns after stopping.

Good for
Adults who meet the prescribing criteria, with a clinician.
Not for
Anyone outside the approved criteria, and some medical histories; a clinician will check.
Risks
Nausea and other digestive effects; rarer serious risks; muscle loss without strength training and protein.
Insurance
Coverage varies widely; ask your plan.
Typical cost
$25–$1,350 a month, by coverage and productAn estimate, still being checked. Ask for the full price, and check your coverage, before you book.

Questions to ask

  1. Am I eligible, and why this medication?
  2. How will we protect muscle?
  3. What's the plan for the long term, and if I stop?
  4. Is this an FDA-approved product?

General education, not medical advice. Choose licensed providers, and talk to a doctor if you have a health condition, are pregnant or take medication. Medical disclaimer.

We never sell, prescribe or dispense medication, and we prefer licensed providers who use FDA-approved products.

Sources

  1. Wilding et al. (2021), Once-weekly semaglutide in adults with overweight or obesity, NEJM
  2. FDA: concerns with unapproved GLP-1 drugs
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